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IHC guides.

Source-reviewed explanations of marker comparisons and interpretation limits. Product links lead only to verified catalogue records.

SOURCE-REVIEWED GUIDE

SOX10 vs S100 in IHC

Both stains can support melanocytic or Schwannian differentiation, but their staining patterns and background differ. Neither is specific enough to settle a case alone.

Reviewed
SOURCE-REVIEWED GUIDE

TTF-1 vs Napsin A in IHC

TTF-1 is a nuclear marker and Napsin A is a cytoplasmic marker. Their combined interpretation can help in selected lung adenocarcinoma workups, with important exceptions.

Reviewed
SOURCE-REVIEWED GUIDE

Ki-67 in Immunohistochemistry: What the Marker Shows

Ki-67 staining estimates the fraction of cells in the active cell cycle. The reported labeling index depends on which cells and areas are counted.

Reviewed
SOURCE-REVIEWED GUIDE

CK7 vs CK20 in IHC

CK7 and CK20 are cytokeratin stains often considered as a pair. Their pattern can orient a differential, but it cannot establish a primary site on its own.

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SOURCE-REVIEWED GUIDE

ER vs PR in IHC

ER and PR are distinct hormone-receptor IHC tests. Both are assessed in tumor nuclei, but current breast-cancer reporting guidance gives ER-low results a specific category.

Reviewed