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MARKER / TTF-1

TTF-1 antibodies for IHC.

1 verified product currently listed.

Reviewed

What TTF-1 staining shows

TTF-1 (NKX2-1) is a nuclear transcription factor expressed in lung and thyroid tissue. Its immunohistochemical signal is assessed in nuclei. In the thyroid setting, the cited review discusses TTF-1 as part of a marker panel rather than a stand-alone site-of-origin test.[1][2]

TTF-1 alongside Napsin A

Lung immunohistochemistry guidance discusses TTF-1 together with Napsin A in selected workups. Their staining patterns differ: TTF-1 is nuclear, whereas Napsin A is cytoplasmic. Interpretation depends on the specimen and the wider clinical and morphologic context.[2]

Products in the ReagentScope catalogue

ReagentScope lists the verified Bio SB TTF-1 8G7G3\1 antibody as a clone-level product record. The linked product page contains its manufacturer specifications and source review.[3]

References and sources

  1. Immunohistochemistry in the pathologic diagnosis and management of thyroid neoplasms (scientific reference)
  2. Best practices recommendations for diagnostic immunohistochemistry in lung cancer (scientific reference)
  3. Bio SB TTF-1 8G7G3\1 (PI6006) (manufacturer product information)